Posted by 4WD on November 17, 2005, at 21:51:24
In reply to Questions re Seroquel and re estrogen (Lar? SLS?), posted by Racer on November 16, 2005, at 11:01:10
I can't suggest anything regarding the Clomid effect, however, I do know for sure that levels of estrogen and particularly progesterone have a distinct effect on my mood. I have taken several different formulations of HRT and have found that some forms of progesterone intensely increase my depression and anxiety.
I can guess that when your estrogen levels are high, your progesterone levels are low, both relatively and absolutely. If the Clomid increases your estrogen levels, then your ratio of estrogen to progesterone would increase. I know I feel better on estrogen and worse on progesterone. So it could be the ratio of estrogen to progesterone in your body that is making the difference.
I've done some searching on the web and here at Babble and have found many reports of people who got bad depression and anxiety from progesterone.
This may at least be some clue.